Essential Evidence-Based Medicine, Volume 1

Front Cover
Cambridge University Press, Jun 17, 2004 - Medical - 381 pages
0 Reviews
Evidence Based Medicine (EBM), using the best evidence in the literature for the best care for an individual patient, sounds very simple. Yet, most medical students and physicians do not have the mathematical background or training to critically evaluate published research. This 'users guide' to EBM helps you become a more discriminating reader of the medical literature, and better equipped to apply EBM in practice. This is an ideal introductory text for medical students and all health-care professionals.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

A brief history of medicine and statistics
1
What is evidencebased medicine?
9
Causation
17
The medical literature an overview
22
Searching the medical literature
30
Study design and strength of evidence
52
Instruments and measurements precision and validity
62
Sources of bias
74
Bayes theorem predictive values posttest probabilities and interval likelihood ratios
222
Comparing tests and using ROC curves
237
Incremental gain and the threshold approach to diagnostic testing
242
Sources of bias and critical appraisal of studies of diagnostic tests
254
Screening tests
267
Practice guidelines and clinical prediction rules
276
Decision analysis and quantifying patient values
288
Costeffectiveness analysis
304

Review of basic statistics
87
Hypothesis testing
102
Type I errors and number needed to treat
113
Negative studies and Type II errors
122
Risk assessment
132
Multivariate analysis
145
Randomized clinical trials RCTs
150
Scientific integrity and the responsible conduct of research
162
Applicability and strength of evidence
170
An overview of decision making in medicine
179
Sources of error in the clinical encounter
196
The use of diagnostic tests
206
Utility and characteristics of diagnostic tests likelihood ratios sensitivity and specificity
211
Outcome analysis
312
Metaanalysis and systematic reviews
319
Levels of evidence and grades of recommendations
329
Overview of critical appraisal
334
Formulas
337
Commonly used statistical tests
340
Proof of Bayes theorem
343
Using balance sheets to calculate thresholds
345
Glossary
347
Bibliography
361
Index
373
Copyright

Other editions - View all

Common terms and phrases

Popular passages

Page 366 - Feinstein AR, Sosin DM, Wells CK. The Will Rogers phenomenon. Stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer.

References to this book

About the author (2004)

Dr. Mayer is a Professor of Emergency Medicine and the Theme Leader of the Evidence Based Health Care course at Albany Medical College in Albany, New York. He has been practising emergency medicine for twenty-four years. For the last 10 years he has developed and taught a required four-year course called Evidence Based Health Care at Albany Medical College. He has been a tutor at Evidence Based Health Care seminars around the world and has spoken frequently about teaching Evidence Based Medicine to educators, medical school faculty, undergraduate medical students, and residents at conferences internationally and in the USA.

Bibliographic information