Essential Evidence-Based Medicine
Evidence Based Medicine (EBM), using the best evidence in the literature for the best care for an individual patient, sounds very simple. Yet, most medical students and physicians do not have the mathematical background or training to critically evaluate published research. This 'users guide' to EBM helps you become a more discriminating reader of the medical literature, and better equipped to apply EBM in practice. This is an ideal introductory text for medical students and all health-care professionals.
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absolute risk analysis association blood calculate cancer case—control cause chapter clinical question clinically important clinician Cochrane Collaboration Cochrane Library cohort studies confidence intervals considered cost cost-effectiveness database death decision tree determine diagnostic test drug effect effect size evaluate evidence evidence-based medicine example exposure false positive gold standard guidelines hypothesis increase intervention Journal likelihood ratios look measure medical literature meta-analysis mortality negative test normal number needed occurs odds ratio outcome of interest patients physicians placebo population positive test post-test odds post-test probability potential practice predictive value present pretest probability probability of disease problem PubMed relative risk risk factor ROC curves rule sample screening test sensitivity and specificity standard deviation statistical tests statistically significant strategy strep throat subjects symptoms systematic reviews Table test result treat treatment threshold Type I error validity variables