Essentials for Animal Research: A Primer for Research Personnel
DIANE Publishing, Dec 1, 1996 - 84 pages
Includes a basic understanding of the regulatory process and the means by which compliance can be assured; an understanding of the basic principles of controlling pain and distress, preventing intraoperative infection, and assuring a humane death in the animals used; and an awareness of the responsibilities one assumes when choosing to use lab. animals. Contents: regulations and requirements; alternative methodologies; animal care and use; principles of anesthesia, analgesia, and aseptic technique; perioperative care; euthanasia; organizations, associations, and societies; and references.
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AAALAC AGRICOLA database alternative analgesia analgesic and/or anesthesia anesthetic agents anesthetic protocol Animal Resources Animal Welfare Act Animal Welfare Information animal’s appropriate aseptic technique barbiturate Biomedical Research cage cats cause Chapter chemical Committee contamination depression disease dogs drape drugs effect endotracheal tube environment equipment euthanasia euthanatized evaluate experimental factors Federal genetic glove Guide Halothane Health Service Policy Humane hypothermia IACUC ILAR infection institutional veterinarian intubation involved ketamine Laboratory Animal Science mals manual ment mice minimize monitored National Agricultural Library nonexperimental variables number of animals pain and distress pain or distress performed perioperative perioperative care personnel postoperative Postoperative Care potential principal investigator procedures rabbits rats recommendations recovery reduce the numbers reflex regulations research facility respiratory response rodents scrub small animals species sterile surgery surgical Taylor Bennett temperature testing tion tissue tive U.S. Department Veterinary Anesthesia Washington Welfare Information Center xylazine
Page 8 - US Government Principles for the Utilization and Care of Vertebrate Animals Used in Test-ing, Research, and Training" (included as an appendix to the NIH Guide).
Page 30 - The principal investigator has considered alternatives to procedures that may cause more than momentary or slight pain or distress to the animals, and has provided a written narrative description of the methods and sources, e. д., the Animal Welfare Information Center, used to determine that alternatives were not available...
Page 81 - Consortium for Developing a Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching, 309 W.
Page 12 - ... horses not used for research purposes and other farm animals, such as. but not limited to livestock or poultry, used or intended for use as food or fiber, or livestock or poultry used or intended for use for improving animal nutrition, breeding, management, or production efficiency, or for improving the quality of food or fiber. With respect to a dog. the term means all dogs including those used for hunting, security, or breeding purposes: (h) The term "exhibitor...
Page 7 - Any means of euthanasia employed must be consistent with the recommendations of the American Veterinary Medical Association Panel on Euthanasia unless the investigator is able to justify any deviation on scientific grounds to the satisfaction of the IACUC.
Page 12 - animal" means any live or dead dog. cat, monkey (nonhuman primate mammal), guinea pig, hamster, rabbit, or such other warmblooded animal, as the Secretary may determine Is being used, or is intended for use, for research, testing, experimentation, or exhibition purposes...
Page 30 - The amendment directed the secretary to develop standards "for animal care, treatment, and practices in experimental procedures to ensure that animal pain and distress are minimized...
Page 12 - Replacement (means) the substitution of insentient material for conscious living higher animals. Reduction (means) reduction in the number of animals used to obtain information of given amount and precision. Refinement (means) any decrease in the incidence or severity of inhumane procedure (ie, pain or suffering) applied to those animals which still have to be used."4' These are goals that both utilitarians and supporters of the Modified Innocence Principle can endorse.
Page 61 - State whether this method is consistent with the recommendations of the Panel on Euthanasia of the American Veterinary Medical Association. If not, presents a justification for not following the recommendations.
Page 69 - ... 23rd of this year, a sum at least equal to this needs to be appropriated. The additional $750,000 for the mandated information service at the National Agricultural Library will bring about savings in government expenditures far greater than its cost. To quote the new amendments: (e) The Secretary shall establish an information service at the National Agricultural Library. Such service shall, in cooperation with the National Library of Medicine, provide information — (1) pertinent to employee...