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INTRODUCTION AND SCOPE
NUMBERS IN TOXICOLOGY
BIOLOGIC FACTORS THAT INFLUENCE TOX
13 other sections not shown
abnormal absorption acetylcholine acid active anesthetic antibody antidotal antigen barbiturate biologic mechanism biologic specimens biologic systems biologic tissue biotransformation body carcinogenic chem chemical agent chemical-induced compound curve Dicumarol drug metabolizing Drug Toxicity effects of chemicals enzyme enzyme systems example excretion experimental exposure factors fluid foreign chemicals formation function gastrointestinal tract genetic hapten harmful effects hemoglobin humans icals immune inactivation induced inhibition insect insecticides intestine intoxication introduction into biologic ionized isoniazid kidney laboratory animals lethal effect lipid liver mammals membrane metabolic transformation methemoglobin mg/kg microsomal mutant non-ionized form nonspecific normal obtained occur offending chemical oral oxidation penicillin pesticides Pharmacol pharmacologic effect pollution present primaquine procedures produce Prontosil protein rats react receptor respiratory response result route of administration selectively toxic skin soluble species stomach studies substances substrate succinylcholine sulfanilamide sulfonamides teratogenic therapeutic therapy tion tolerance toxic effect toxicity toxicity tests toxicology translocation undesirable urine