Exploring Bioinformatics: A Project-based Approach
Exploring Bioinformatics: A Project-Based Approach Is Intended For An Introductory Course In Bioinformatics At The Undergraduate Level. Through Hands-On Projects, Students Are Introduced To Current Biological Problems And Then Explore And Develop Bioinformatic Solutions To These Issues. Each Chapter Presents A Key Problem, Provides Basic Biological Concepts, Introduces Computational Techniques To Address The Problem, And Guides Students Through The Use Of Existing Web-Based Tools And Existing Software Solutions. This Progression Prepares Students To Tackle The On-Your-Own Project, Where They Develop Their Own Software Solutions. Topics Such As Antibiotic Resistance, Genetic Disease, And Genome Sequencing Provide Context And Relevance To Capture Student Interest.
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Chapter 1 Exploring Bioinformatics
Exploring Genetic Disease
Investigating Antibiotic Resistance
Clues to Protein Function
The Human Genome
Finding Genes in the Human Genome
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allele amino acids amino-acid sequence antibiotics array assembly bacteria base base-pairs BioBackground bioinformatics BLAST cell Chapter characters ClustalW clusters column companion website complete consensus sequence database determine distance DNA molecule DNA sequence encode eukaryotic evolutionary example Exploration FASTA format Figure fold fragments function G G G GenBank grid Guided Project hash table human genome hydrophobic identify implement look loop MAGIC Tool match merge method microarray data mismatch molecular molecular clock mRNA mutation nucleotide nucleotide sequence output overlap phylogenetic tree plasmid prediction prokaryotic promoter protein alignments protein sequences Putting Your Skills reading frame region represents Running the Program score secondary structure Shine-Dalgarno sequence shotgun sequencing sickle-cell similar Skills into Practice species start codon statement Step stop codon strand string subroutine substitution matrix text file transcription Understanding the Problem variable