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The Impact of Psoralen Photoadducts on Cells
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3,4-monoadducts 8-methoxypsoralen 8-MOP and UVA 8-MOP photoadducts 8-MOP/UVA treatment acid activity adducts agents angelicins antibody antigens apoptosis binding constant Biol blood Cancer CD4 cells cells treated cellular chapter class I MHC clinical trial clones cutaneous T-cell lymphoma cytokine cytokine profile cytotoxic Dall'Acqua demonstrated disease DNA binding DNA damage Edelson RL effects enhanced extracorporeal extracorporeal photochemotherapy furocoumarins Gasparro FP genes Hospital human immunodeficiency virus human lymphocytes immune response immune system immunogenicity Immunol immunosuppressive induced infection inhibition initial Invest Dermatol irradiation keratinocytes lymph nodes methoxsalen MHC molecules mice molecular events monoadducts and crosslinks murine mutagenic mutations mycosis fungoides NF-kB ng/ml 8-MOP photoactivated photoadduct formation Photobiology Photochem Photobiol 1993 photochemistry photochemotherapy photopheresis PI cells proteins psoralen psoralen-DNA psoriasis PUVA repair shown singlet skin specific studies survival therapeutic therapy tion transcription factor transplant treated cells ultraviolet upregulation UVA dose viral vitro vivo wavelength