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Multiple epiphyseal dysplasia
B With predominantly metaphyseal involvement 5 Achondroplasia classical type
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A. G. Apley abnormal achondroplasia adult Aetiology affected American Journal anaemia appearance areas associated autosomal dominant autosomal recessive autosomal recessive inheritance Bone & Joint bone lesions calcification calcium cartilage cells changes characteristic childhood chondrodysplasia chronic clavicles Clinical and radiographic congenital cortex Courtesy of Dr defect deformity density develop diaphyseal Differential diagnosis disorder dwarfism enlarged epiphyseal dysplasia epiphyseal plate femoral femur generalised genetic homocystinuria Hurler syndrome hyper hyperparathyroidism hypocalcaemia Hypophosphatasia infancy involved irregular Joint Surgery Journal of Bone leukaemia limb long bones lumbar Maroteaux marrow McKusick Metabolic metacarpals metaphyseal metastases mucolipidoses mucopolysaccharide multiple normal occur ossification osteo osteogenesis imperfecta osteomalacia osteoporosis Paget's disease particularly Pathological fractures patients Pediatrics pelvis periosteal reaction phalanges population incidence Progress and complications Pyrford radiographic features Radiology rare renal reported ribs rickets sclerosis sclerotic scoliosis secondary severe short signs skeletal skull spine Spranger syphilis tarda thickening tibia treatment tumours usually vertebrae vertebral bodies vitamin