Fetal Alcohol Abuse Syndrome

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Springer Science & Business Media, Jul 31, 1998 - Medical - 260 pages
My initial purpose in writing this book was to offer readers an update of my book Fetal Alcohol Syndrome and Fetal Alcohol Effects (Plenum, 1984), which con tained a broad overview of the history (actually the absence of any history) ofthe awareness of alcohol's teratogenic potential; a review of alcohol's pharmacology, especially with respect to pregnancy; a survey of the physical and behavioral effects of prenatal alcohol exposure; and an overview of the mechanisms sus pected of being responsible for those effects. I have omitted most of the previously examined historical and pharmacologi cal information because not much of what was previously discussed needed revision. On the other hand, because much more has been learned about the consequences of prenatal alcohol exposure and its potential mechanisms of action, I have considerably expanded my discussion of these topics. In doing so, I have attempted to include as much new material as possible without (I hope) being overly pedantic and thereby losing the proverbial forest for the trees. No book is ever entirely neutral in the topics it discusses, the issues it raises, or in its conclusions. In sifting through hundreds and oftentimes thousands of articles, writers have to choose which facts to emphasize and which to ignore. Every idea cannot be chronicled and every article cannot (and should not) be cited. In going about the business of picking and choosing, however, a writer has an obligation to present the arguments for and against a particular conclusion.

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Why Fetal Alcohol Abuse Syndrome?
Spontaneous Abortion
Perinatal Problems
Miscellaneous ARBEs
Growth Retardation
Craniofacial Anomalies
AlcoholAbuseRelated Malformations
Neurodevelopmental Abnormalities Structural and Sensory
Neurodevelopmental Abnormalities Behavioral and Cognitive
The American Paradox
Permissive and Provocative Factors in FAS
Conclusions and Implications

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Page 3 - For there exists a great chasm between those, on one side, who relate everything to a single central vision, one system less or more coherent or articulate, in terms of which they understand, think and feel— a single, universal, organizing principle in terms of which alone all that they are and say has significance...
Page 248 - The effects of prenatal alcohol and marijuana exposure: disturbances in neonatal sleep cycling and arousal.
Page 251 - Streissguth AP, Clarren SK, Jones KL. Natural history of the fetal alcohol syndrome: a 10-year follow-up of eleven patients.
Page 252 - Sulik, KK, and Johnston, MC Sequence of developmental alterations following acute ethanol exposure in mice: Craniofacial features of the fetal alcohol syndrome. Am J Anat 166:257-269, 1983.

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