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The Molecular Biology of the Fragile X Mutation
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abnormalities adults affected males allele analysis autism behavior carrier females cells child Clin clinical clonidine cognitive Cronister culture cytogenetic deficits developmental disorder E. C. Jenkins families folate folic acid fra(X fra(X)-positive fragile site fragile site expression fragile X chromosome fragile X syndrome fragile-X frequencies of expression Froster-Iskenius Fryns G. R. Sutherland gene genetic counseling Hagerman Hecht heritable fragile sites heterozygotes heterozygous Howard-Peebles human chromosomes hyperactivity hypotonia inactivation individuals inheritance intervention Laird linkage locus lymphocytes M. G. Mattei macroorchidism Martin-Bell syndrome Ment mentally impaired mother motor mutation neuropsychological nonimprinted nonpenetrant males normal Partington patients phenotype population prenatal diagnosis problems Psychiatry R. J. Hagerman recombination Renpenning replication reported risk seizures sensory integrative sequence Sherman Sherman paradox short stature significant social specific studies testing therapist therapy thymidine tion Tommerup transmitting males treatment Turner W. T. Brown X-inactivation X-linked mental retardation XLMR