From Alchemy to IPO: The Business of Biotechnology

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Basic Books, 2001 - Business & Economics - 253 pages
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"A tour-de-force for anyone who is interested in the biotech industry. I applaud the enormous achievement of Cynthia Robbins-Roth."-Frederick Frank, Senior Managing Director & Vice Chair, Lehman Brothers"From Alchemy to IPO tells the dramatic story of this revolutionary industry as only an insider can."-George Rathmann, President and CEO, ICOS Corporation, Chairman Emeritus, AmgenWritten by a well-known industry insider, From Alchemy to IPO addresses the coming-of-age of biotech products and companies and traces the history of biotechnology from its early inception in the seventies to today's heyday of new solutions and breakthrough treatments. It describes the amazing entrepreneurial trail of product development, novel business models, and critical trials that eventually pave the way to market. This is the first book to accurately record the inner workings of an industry-biotechnology-that's on the verge of living up to its monumental promise to change the world as we know it.
 

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Contents

Biotech in the Beginning
4
Genentech The Leader of the Pack
14
The Amgen Story
32
The Exception to Every Rule Genzyme
44
The Other Biotech Monoclonal Antibodies
49
Biotech Star Wars
60
The Human Genome Project
68
Tools for Genome Studies BioChips and Microarrays
74
The Drugs Development Process From Test Tubes to Patients
112
Speed Bumps and Brick Walls Clinical Trial Design
125
Biotech Bankers
132
Initial Public Offerings
147
Creative Financing
156
Corporate Partners and the Urge to Merge
162
The Biotech Stock Landscape
184
Picking the Right Stocks
199

Treating Disease at the Gene Antisense Drugs
83
Gene Therapy
86
Following the Path of Communication Signal Transduction
90
BrandNew Knees Tissue Engineering and Cell Replacement
93
Building New Drugs Combinatorial Chemistry
98
Agricultural Biotechnology
106
Biotech Timeline
220
Biotechnology Derived Products on the Market
225
Biotech Web Sites and Resources
231
BioVenture Consultants Biotech Stock Report
236
Index
244
Copyright

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About the author (2001)

Cynthia Robbins-Roth, Ph.D., is the founder of BioVenture Consultants, which provides strategic planning and financial assessment to biotech start-ups, pharmaceutical companies, and venture-capital firms. Her biotech column appears regularly in Forbes magazine, and Forbes ASAP recently named her one of the top twenty-five biotech all-stars of 1999. She lives in San Mateo, California.

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