From Egg to Embryo: Determinative Events in Early Development
This book is about the development of the animal embryo starting from the fertilised egg. The emphasis is on the problem of pattern formation: how cells in different regions of the embryo become programmed to form the various structures of the body in the correct relative positions.
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The concepts of experimental embryology
a hierarchy of developmental decisions
Insect embryos and the genetic program of early development
Development with a small cell number
The mouse and its amniote relatives
The problems of early development and the means for their solution
Gradient models for embryonic induction and regulation
Thresholds and repeating patterns
4-cell stage abdominal activity adult amphibian amphibian embryo archenteron arise become behaviour biochemical Biol blastocoel blastocysts blastomeres blastopore blastula body plan cell division cell number cell types cellular chick chromosome cleavage clonal clone comb plates concentration ctenophore cytoplasm cytoplasmic localisation defects developmental decisions differentiation diffusion dorsoventral Drosophila early development early embryo ectoderm embryo embryology endoderm epidermis experimental experiments explants extra-embryonic fate map fertilised egg formation gastrula gene genetic germ anlage germ band gradient model graft gynandromorph inhibitor insect interactions invagination involved isolated larva later marginal zone mechanism membrane mesentoblast mesoderm mesothorax micromeres morphogen Morphol mosaic mouse embryo muscle mutants neural induction neural plate neurula normal development notochord nuclei organiser pattern polar lobe possible posterior primitive streak produce proportions prospective regions protein regional specification regulation sea urchin segments sequence shown somites stem cell structures substances synthesis teratocarcinoma tion tissue trophectoderm vegetal ventral vertebrate yolk
Page 229 - Martin, GR and Evans, MJ (1975) Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro, Proc. Natl. Acad Sci. USA 11.
Page 230 - Nieuwkoop, PD 1973. The organization center of the amphibian embryo: Its origin, spatial organization and morphogenetic action. Adv.
Page 233 - Sulston, JE, and Horvitz, HR (1977). Post-embryonic cell lineages of the nematode, Caenorhabditis elegans.