Genetic Engineering, second edition has been thoroughly revised and updated to address these changes and in particular to integrate more clinical relevance. Key changes include a completely new chapter on the diagnosis of human genetic diseases using PCR, and descriptions of new diagnostic procedures such as DNA micro-array analysis.
Genetic Engineering, second edition is an invaluable guide to biology and medical students, clinicians and researchers involved in the field of molecular genetics.
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lowresolution mapping of genomic DNA
determining the structure of genes
4 other sections not shown
agarose alleles amino acid amplified analyzed annealing bacterial base pairs binding cDNA clone cDNA libraries cell lines chromosome cleavage cleaved codon coli complementary containing copy cystic fibrosis denatured detected diagnosis differential disease DNA molecule DNA polymerase DNA sequence DNA sequence analysis domain double-stranded DNA EcoRI encoded eukaryotic Factor VIII Figure fluorescent function gel electrophoresis gene expression genomic clone genomic DNA heteroduplexes homologous recombination hybridization identify insert introns isolated ligation mammalian cells mapping marker method mismatched molecular mouse mRNA mRNA population normal nucleic acid nucleotides oligonucleotide P-gal packaging pBluescript PCR product phage plasmid point mutations poly(A polyacrylamide gel polymorphism position possible primer prokaryotic protein region repeats replication Reporter oligo residue restriction enzyme ribosome sample screening single-stranded Southern blotting Southern transfer specific splicing strand structure synthesis target DNA techniques template tissue transcription factors transformation transgenic transgenic mice translation tRNA vector molecules viral VNTRs yeast