Genetic disorders: prevention, treatment, and rehabilitation; report of a WHO scientific group
World Health Organization. Scientific Group on Genetic Disorders: Prevention, Treatment, and Rehabilitation, World Health Organization
World Health Organization, 1972 - Medical - 46 pages
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Prevention and treatment
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amniocentesis anencephaly Ashkenazi Jews Autosomal biochemical cause cells centres chromosomal aberrations chromosomal disorders cleft clinical congenital malformations cytogenetic deficiency detection diet Down's syndrome drug environmental factors enzyme example facilities FAO/WHO Expert Committee fetal fetus frequency of genetic G6PD gene frequency genetic counselling genetic disease GENETIC DISORDERS Genetic registries genetically determined genetically heterogeneous genotype hereditary metabolic disease heterozygotes heterozygous high birth frequency homozygotes identified increase individuals ischaemic heart disease Joint FAO/WHO Expert lethal Librairie long-term mass screening maternal age maternal effects matings medical genetics Mendelian methods multifactorial traits mutagens mutant gene mutation mutation rate needs offspring P.O. Box paediatric hospital patients Pesticide phenotype phenylketonuria possible pregnancy prenatal diagnosis prophylactic treatment public health pyloric stenosis rare recessive trait recurrence reduction relaxed selection reproductive fitness risk Scientific Group screening programmes selective termination sickle-cell anaemia specific Tay-Sachs disease techn techniques therapy tions treatment of genetic variation WldHlth Xeroderma pigmentosum