Germinal Centers in Immune Responses: Proceedings of a Symposium Held, at the University of Bern, Switzerland, June 22–24, 1966
Springer Berlin Heidelberg, Jan 1, 1967 - Medical - 499 pages
In the last few years the study of germinal centers of the lymphoid tissue has progressed at an accelerated pace. Questions about their role and their significance in immune responses that could not be answered, mainly because of tedmicallimitations, are presently approached experimentally from many different directions. Hypotheses, some more than half a century old, receive renewed attention. At this time, members of the Biology Division, Oak Ridge National Laboratory, U.S.A., and of the Institute of Pathology, University of Bern, Switzerland, decided to bring together workers interested in the field. The Conference was held in Bern, June 22-24, 1966, and included fifty-seven contributions which were discussed at length. The range of interest extended from phylogenesis and anatomy to studies on cell proliferation, immunohistochemistry, cancer research and radiobiology. The aim of this broad coverage was to combine all available information on the role of germinal centers in immune responses in a single package, instead of leaving it scattered around in reports dealing with divergent immunological problems. This attempt is reflected in the present book. A rather large space has been devoted to the lively discussions which followed the reports, the volume of most of which had been voluntarily limited. The discussions are not reported verbatim but care has been taken to insure neutrality and objectivity in the necessary adaptation of the shortened transcription. We have been very fortunate indeed, to have Drs.
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Ontogenetic Development of the Germinal Centers and Their Function Relationship
Germinal Centers in the Tonsilla Caecalis Relationship to the Thymus and the Bursa
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24 hours agammaglobulinemia allograft animals antibody antibody formation antibody production antibody response antigen antigenic stimulation appearance Biol blast cells blood bone marrow bursa of Fabricius cellular chickens CoNGDoN cortex cytoplasm differentiation disease dose experimental fluorescent foci follicular germfree germinal center cells germinal centers globulin graft HANNA hemagglutinin hemolytic histological homograft immune response immunoglobulins Immunol induced injection of Thymidine-*H intravenous irradiation labeled cells large pyroninophilic cells lymph nodes lymphatic tissue lymphoid cells lymphoid follicles lymphoid system lymphoid tissue macrophages medullary mitotic morphological mouse N.Y. Acad neonatally thymectomized nodules normal observed PARRoTT peripheral Peyer's patches plasma cells primary Proc proliferation protein rabbits rats reaction red pulp reticular cells secondary response serum small lymphocytes specific spleen spleen cells splenic stained studies target cells thoracic duct THoRBECKE thymectomized mice thymic thymus thymus-dependent area tingible bodies tion titers tonsil tumor vitro white pulp X-irradiation y-globulin zone