The Hierarchical Genome and Differentiation Waves: Novel Unification of Development, Genetics and Evolution, Volume 1
Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.
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Flip Animation of the Ectoderm Contraction Wave
Proposition Page Numbers
A scanning electron micrograph SEM of a fertilized human egg
The stages of embryonic development of a urodele salamander
Index of Propositions 1252
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actin active amphibian animal apical Appendix asymmetric axolotl biology Bjorklund & Gordon Bjorklund & Nieuwkoop blastomeres blastopore brain cell division cell state splitter cell types cellular centrosomes changes chromosome ciliates cleavage complex components concept correlation cortex cortical cytoplasm cytoskeleton determination developmental differentiation cascades differentiation tree differentiation waves dorsal Drosophila duplication ectoderm ectoderm contraction wave embryo embryogenesis embryology epigenetic etal evolution evolutionary expansion wave Figure function gastrulation gene expression genetic genome Gordon & Brodland hierarchical Holtfreter homeobox homologous interactions intermediate filaments involved Jacobson larva launching lineage macroevolution mechanical membrane mesoderm microfilament microfilament ring microtubules molecular molecules morphogenesis morphogenetic morphological mosaic mutations nematodes neural plate Nieuwkoop nuclear nucleus occur pattern perhaps phenotype physical polarity possible primary neural induction problem propagation Proposition proteins region regulation signal single cell spatial species Spemann stage step of differentiation structure suggested terminal branch theory tissue trajectory Waddington Wolpert Xenopus