HLA and the Maternal-Fetal Relationship

Front Cover
Landes, 1996 - Medical - 192 pages
0 Reviews
This book is about maternal-fetal interactions during pregnancy that depend on cell surface structures termed HLA. When foreign to the host, HLA stimulate massive graft rejection responses. There is little if any evidence for such a response at the maternal-fetal interface. This may be due to special controls on the expression of HLA in placentas and their associated membranes, which sequester the embryo from maternal immune cells. This book provides the reader with an understanding of HLA and its potential to stimulate graft rejection, describes recent experiments that have provided new insights into HLA gene selection and regulation during development, and discusses the potential implications for fertility in healthy women as well as patients with immune disorders.

From inside the book

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Features of the MaternalFetal Interface
1
Current Theories on Protection of the Fetal Semiallograft
27
HLA Class I Genes and Products
51
Copyright

6 other sections not shown

Common terms and phrases

Bibliographic information