CRC Handbook of Animal Models for the Rheumatic Diseases, Volume 1

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CRC Press, Sep 30, 1988 - Medical - 256 pages
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Detailed methods of the most widely used and best established animal models and related approaches to the study of rheumatic diseases and their treatment are presented in this major reference book. The detailed description of each model allows the reader to select the model most appropriate for his research and to reproduce the model without resorting to additional references. In addition, other methods for induction of the model, sources for procurement of suitable animals and validation of the model are highlighted. Methods for eliciting non-spontaneous phenomena, follow-up examinations and data collection are also described. Specific techniques such as joint-injection, obtaining synovial tissue, methods of assessment and similar non-specific information are emphasized. This easy-to-read resource text is essential for scientists, graduate students, research assistants, physicians and other invbestigators who use animal models for the study of rheumatic diseases.
 

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Contents

CollagenInduced Arthritis in Rats
17
Passive Collagen Arthritis Induced by Affinity Purified Anticollagen IgG
29
Lactobacillus casei Cell WallInduced Arthritis in Rats
41
Comparative Studies between Adjuvant Type II Collagen and Streptococcal
49
W Cooke
79
Inflammation Induced by 6Sulfanilamidoindazol
93
Caprine ArthritisEncephalitis Virus
101
MycoplasmaInduced Arthritis in Rabbits
109
The Subcutaneous AirPouch Model of Inflammation
125
The Utility of the MRL1 Mouse for Detecting AntiArthritic Drugs
137
Coxsackievirus B1Induced Murine Polymyositis
147
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