Handbook of Dendritic Cells: Biology, Diseases and Therapies
Manfred B. Lutz, Nikolaus Romani, Alexander Steinkasserer, Ralph M. Steinman
Wiley, Mar 17, 2006 - Medical - 1226 pages
This is the most comprehensive handbook on dendritic cells, featuring an introduction by Ralph M. Steinman and written by top experts. In three volumes, it covers all aspects from molecular cell biology to clinical applications, highlighting the role of dendritic cells in fighting cancer, virus infections, and autoimmune diseases.
The first section on cell biology looks at dendritic cell development, circulating cells, T cell priming, Th1 and Th2 decision and CTL priming. A second part on dendritic cells in disease deals with parasites, bacteria, viruses, autoimmunity, allergies, asthma and cancer. The final section on therapeutic applications includes viral infections and antigen delivery.
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ACAID activation adaptive immune antibody antigen antigen presentation apoptotic apoptotic cells Banchereau binding Biol blood monocytes bone marrow CCR2 CD1d CD8+ cellular chemokine receptor CLRs culture cytokines DC and IPC DC subsets DC subtypes DC-SIGN dendritic cells differentiation effector function gene expression GM-CSF IFN-Y immature DC immune responses Immunology induce infection inflammation inflammatory innate immune interaction interferon Langerhans cells langerin ligand lineage lymph nodes lymphocytes lymphoid organs macrophages markers mature DC mediated MHC class mice microbial migration molecules monocytes mouse murine myeloid myeloid DCs Nat Immunol natural killer NKT cells numbers pathogens pathway pDCs/IPCs pentraxin peripheral blood phenotype plasmacytoid dendritic cells population precursors produce progenitor cells protein PTX3 recognition regulation Rev Immunol role scavenger receptor Shortman signaling spleen SR-A Steinman stimulation Streilein studies T-cell tion tissues Toll-like receptors transcription factor tumor type 1 IFN viral vitro vivo