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FACTORS AFFECTING THE CHOICE OF DRUG AND
PRACTICAL ASPECTS IN THE SELECTION
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achieve acid action activity acute addition administration adverse agents analgesic antiinflammatory drugs antimalarial drugs appear Arthritis Rheum aspirin associated blood cause cell changes choice chronic clinical combination common compliance compounds Consequently continued corticosteroids course daily decrease derivatives develop diagnosis disorders dosage dose early efficacy example factors fever Figure four frequently function given gold half-life ibuprofen important improvement increased individual indomethacin inflammation inflammatory inhibit initial injections involvement joints juvenile rheumatoid arthritis less levels major manifestations measures medication months naproxen nonsteroidal normal NSAIDs occur onset pain particular patients penicillamine peripheral physician plasma potential present problems produce progressive psoriatic rarely reactions renal reported response result rheumatic diseases Rheumatol salicylate seen serum severe side effects specific studies suggest suppression symptoms syndrome synovial fluid systemic Table therapeutic therapy tion tissue toxicity treat treatment understanding usually various weeks