Hepatobiliary Diseases: Cholestasis and Gallstone

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M. Acalovschi, G. Paumgartner
Springer Science & Business Media, Mar 31, 2001 - Medical - 174 pages
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In recent years, our knowledge about the pathogenesis, pathophysiology and treatment of hepatobiliary diseases has increased considerably. The molecular basis of cholestatic disorders as well as of gallstone disease is increasingly recognized. This has resulted in improved diagnosis, for instance in hereditary forms of intrahepatic cholestasis, and advances in treatment, for example in primary biliary cirrhosis and other chronic cholestatic disorders. This book, the proceedings of a Falk Workshop held in Cluj-Napoca, Romania, on June 9-10, 2000, brings together contributions from scientists and clinicians to highlight the most recent advances in molecular biology, pathophysiology, diagnosis and therapy of diseases of the hepatobiliary system. World experts cover a broad spectrum of topics from genetic studies to endoscopy and from medical treatment to liver transplantation.
 

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Contents

Molecular basis of bile formation and cholestasis
3
Histopathology of cholestasis
21
lmmunological aspects of chronic cholestatic liver diseases
32
The cholestatic syndrome a clinical approach
42
Cholestasis induced by drugs and toxins
48
Diseases of hepatic transport
54
Mechanisms of action of ursodeoxycholic acid in cholestasis
61
Primary biliary cirrhosis
68
GALLSTONE DISEASE
115
Epidemiology of gallstone disease
117
Pathogenesis of cholesterol gallstones
131
Lifestyle and gallstone prevention
137
Bile acid treatment of gallstones
143
Shockwave lithotripsy of gallstones
146
Nonsurgical treatment of bile duct stones
153
Laparoscopic cholecystectomy incidents and complications
160

Primary sclerosing cholangitis
73
Therapy of extrahepatic manifestations of cholestasis
79
Transplantation for cholestatic liver disease
97

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