Hepatotoxicity: The Adverse Effects of Drugs and Other Chemicals on the Liver

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Lippincott Williams & Wilkins, 1999 - Medical - 789 pages
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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
 

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I was Dr Z secretary for 5 years and learned so much helping edit the book. I miss him dearly and so proud to have the first edition of this book.

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A chemical about the Hepatotoxicity: The Adverse Effects of Drugs and Other Chemicals on the Liver, thst would be the chemicals are also in this book here!

Contents

The Spectrum of Hepatotoxicity
3
Hepatic Metabolism of Foreign Compounds
11
Vulnerability of the Liver to Toxic Injury
41
Expressions of Hepatotoxicity
61
Classification of Hepatotoxins and Mechanisms of Toxicity
111
Hepatotoxic Effects of Ethanol
147
Chemical Hepatocarcinogenesis
177
EXPERIMENTAL HEPATOTOXICITY
199
Hepatotoxicity in the Household
391
The Hepatotoxic Potential of a Polluted Environment
409
IATROGENIC HEPATIC INJURY
425
Anesthetic Agents
457
Psychotropic and Anticonvulsant Agents
483
Drugs Used to Treat Rheumatic and Musculospastic Disease
517
Hormonal Derivatives and Related Drugs
555
Hepatic Injury from the Treatment of Infectious and Parasitic Diseases 589
639

Haloaliphatics Phosphorus Iron and Copper
229
Indirect Cytotoxic Hepatotoxins
255
Toxic Cholestasis
295
ENVIRONMENTAL HEPATOTOXICITY
325
Occupational Toxicity
365
Hepatotoxic Effects of Oncotherapeutic and Immunosuppressive Agents
673
Miscellaneous Drugs and Diagnostic Chemicals
709
Afterthoughts on Hepatotoxicology
743
Glossary of Abbreviations
749
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