History of Vaccine Development

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Stanley A. Plotkin
Springer Science & Business Media, May 11, 2011 - Medical - 349 pages
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Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.

 

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Contents

Introduction
1
Variolation and Vaccination in Late Imperial China Ca 15701911
5
Edward Jenners Role in the Introduction of Smallpox Vaccine
13
Edward Jenner Benefactor to Mankind
21
The Vindication of Jenners Prophesy
27
Pasteur and the Birth of Vaccines Made in the Laboratory
33
Lessons from the Past
47
A History of Toxoids
57
A Historical Debate
151
History of Koprowski Vaccine Against Poliomyelitis
155
Oral Polio Vaccine and the Results of Its Use
167
The Development of IPV
179
The Long Prehistory of Modern Measles Vaccination
189
The History of Measles Virus and the Development and Utilization of Measles Virus Vaccines
199
The Development of Live Attenuated Mumps Virus Vaccine in Historic Perspective and Its Role in the Evolution of Combined MeaslesMumpsRubella
207
History of Rubella Vaccines and the Recent History of Cell Culture
219

A Century of Research End of the Beginning or Beginning of the End?
65
From WholeCell to Subunit Vaccines
73
Bacterial Polysaccharide Vaccines
83
PolysaccharideProtein Conjugate Vaccines
91
History of New Rabies Vaccines
103
The Success of Empiricism Pitfalls of Application and Transition to Molecular Vaccinology
109
A History of Influenza Vaccines
137
The Role of Tissue Culture in Vaccine Development
145
Three Decades of Hepatitis Vaccinology in Historic Perspective A Paradigm of Successful Pursuits
233
Its Development and Progress
247
Developmental History of HPV Prophylactic Vaccines
265
RotaShield
285
Raising the Bar for Vaccine Safety Studies
315
Veterinary Vaccines in the Development of Vaccination and Vaccinology
329
Index
339
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