Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice

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David K. Gardner, Botros R. M. B. Rizk, Tommaso Falcone
Cambridge University Press, Mar 31, 2011 - Medical
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Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice offers a collection of concise, practical review articles on cutting-edge topics within reproductive medicine. Each article presents a balanced view of clinically relevant information and looks ahead to how practice will change over the next five years. The clinical section discusses advances in reproductive surgery and current use of robotic surgery for tubal reversal and removal of fibroids. It looks into the refinement of surgical procedures for fertility preservation purposes. Chapters also discuss non-invasive diagnosis of endometriosis with proteomics technology, new concepts in ovarian stimulation and in the management of polycystic ovary syndrome, and evidence-based ART. The embryology section discusses issues ranging from three-dimensional in-vitro ovarian follicle culture, and morphometric and proteomics analysis of embryos, to oocyte and embryo cyropreservation. This forward-looking volume of review articles is key reading for reproductive medicine physicians, gynecologists, reproductive endocrinologists, urologists and andrologists.
 

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Contents

Use of robotics in reproductive surgery
1
Removal of hydrosalpinges and uterine leiomyoma to improve IVF outcome
11
effect on IVF outcome
18
Impact of uterine cavity abnormalities on IVF and pretreatment cavity evaluation
27
Sperm retrieval techniques
41
New concepts in ovarian stimulation
54
GnRH antagonists in ART
73
Pharmacogenetics of ovarian stimulation in the twentyfirst century
80
Artificial gametes
177
Current status and future trends of the clinical practice of human oocyte in vitro maturation
186
Oocyte and zona imaging
199
Granulosa cells and their impact on human ART
209
selecting the best sperm for IVFICSI treatment
223
Embryo culture in the twentyfirst century
232
Morphometric analyses of embryos
248
towards trophectoderm isolation and blastocyst analysis
260

Noninvasive diagnosis of endometriosis with proteomic technologies
88
Antiangiogenic agents for endometriosis
101
New concepts in the management of polycystic ovary syndrome
110
Adjuvant therapy to increase implantation rates
119
Ovarian hyperstimulation syndrome
127
The evidencebased practice of assisted reproduction
152
Threedimensional in vitro ovarian follicle culture
167
Analysis of the embryonic transcriptome
269
Analysis of embryoderived factors as markers of developmental potential and viability
278
Proteomics analysis of the endometrium and embryo Can we improve IVF outcome?
289
Analysis of embryo metabolism and the metabolome to identify the most viable embryo within a cohort
301
Oocyte and embryo cryopreservation
313
Index
326
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About the author (2011)

David K. Gardner is Head of the Department of Zoology, University of Melbourne, Australia.

Botros R. M. B. Rizk is Professor and Head of the Division of Reproductive Endocrinology and Infertility, University of South Alabama College of Medicine, and Medical and Scientific Director, University of South Alabama In Vitro Fertilization Laboratory, Mobile, AL, USA.

Tommaso Falcone is Professor and Chair of Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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