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Clinical pharmacokinetics and dosing Gregory D Fink
Absorption distribution metabolism
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acetylcholine action potential activity administration adrenergic adrenergic receptors agents agonists amino acid androgen anesthetic antagonists atropine autonomic benzodiazepines binding block blockade blood pressure brain Ca++ calcium cardiac cause cells ceptors channels Chapter chemical cholesterol choline cholinergic clearance clinical compounds concentration of drug crease cyclase decrease depolarization depression disease diuretics dopamine dose enzyme epinephrine estrogen ethanol excretion factors Figure function G protein gene glucocorticoids glycosides half-life heart hormone hypertension increase inhibition inhibitors injection insulin interactions intracellular ions kinase liver MECHANISMS OF ACTION membrane metabolism metabolites molecular molecules muscarinic nerve terminals nervous system neuroeffector junction neurons neurotransmitter nicotinic norepinephrine normal occur opioid oral organs parasympathetic pathways patients penicillin peripheral pharmacokinetic Pharmacology phenytoin plasma concentration produce prostaglandins protein receptors reduced release renal response result serum side effects smooth muscle sodium specific stimulation structure subtypes subunits sympathetic synaptic synthesis target testosterone therapeutic therapy tion tissue toxicity transmitter treat treatment tumor types vascular