Imaging and Intervention in Cardiology
C.A. Nienaber, Udo Sechtem
Springer Science & Business Media, Nov 30, 1995 - Medical - 550 pages
Less than 18 years have passed since the first coronary balloon angioplasty was performed in September 1977 by Andreas Gruntzig. In 1993, 185700 coronary angioplasties were performed in Europe and in many European countries, percutaneous transluminal coronary angioplasty is the most com mon method of myocardial revascularization, well ahead of coronary bypass surgery. This explosive growth of interventional cardiology results from major technological advances. The balloons have been markedly improved with a better profile, excellent trackability, and good pushability. The steer able guide wires are excellent and can reach the most difficult and the most distal parts of the coronary tree. The guiding catheters offer excellent support and good back-up in the ostium. Meanwhile, new tools have been proposed and designed for a "lesion specific" approach. Coronary stenting which is the "second wind" of angioplasty has dethroned most of the so-called new tools and stents are currently implanted in 30-60% of cases. Similar develop ments have occurred in the field of mitral valvuloplasty, ablative techniques in electrophysiology, and in the field of interventions in congenital heart disease. However, these advances would not have been possible without the con comitant development of cardiac imaging. For many interventions, cardiac imaging is an necessary pre-requisite: 1. Imaging is mandatory to identify the lesions needing an intervention. Coronary bypass surgery or angioplasty cannot be performed without prior coronary angiography. However, scintigraphic stress testing is also needed to identify perfusion defects in the area supplied by the diseased artery.
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acute infarction acute myocardial infarction angiography anteroapical area at risk assessment Bergmann calcium cardiac Cardiology clinical Coll Cardiol 1989 contractile dysfunction contractile function coronary artery coronary occlusion correlate decrease demonstrated deoxyglucose early ejection fraction electrocardiogram F-18 deoxyglucose fatty acid Figure following reperfusion Gibbons RJ glucose glucose utilization hibernating myocardium hospital discharge improvement infarct artery injection ischemic isonitrile JAm Coll Cardiol left ventricular ejection left ventricular function LVEF match mechanisms mismatch myocar myocardial blood flow myocardial perfusion defect myocardial perfusion imaging myocardial salvage myocardial stunning myocardium at risk myocytes nondiagnostic electrocardiogram noninvasive normal Nucl oxidative metabolism P.O. Box patients with acute planar positron emission tomography quantification radionuclide radionuclide ventriculography received thrombolytic therapy recovery of stunned regional myocardial regional wall motion reocclusion reperfusion therapy revascularization scintigraphy serial imaging Serial myocardial perfusion sestamibi studies stunned myocardium successful reperfusion technetium-99m thallium therapy for acute thrombolytic therapy tracer ventricular ejection fraction viability
Page vii - Assessment of viability in severely hypokinetic myocardium before revascularization and prediction of functional recovery: The role of echocardiography 279 Luc A.