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abortion activity agglutination allogeneic allograft anti-D antibody antibody production antigens autoimmune B-lymphocytes babies Bagshawe blood group Brit Cancer cell-mediated immunity cellular immunity choriocarcinoma chorionic carcinoma circulation clinical complement complement system complex congenital rubella cytotoxic demonstrated detected disease effect embryo evidence factor fetal fetus genetic gestation gestosis grafts Gynec histocompatibility hormones human humoral hydatidiform mole immune reaction immune response immunisation immunogen immunoglobulin immunological implantation incidence incompatibility induced infants infection infertility inhibition intrauterine involved isoimmunisation Lancet leucocyte levels lymphocytes lymphoid macrophages malignant maternal mechanism mediated membrane molecule mother mouse myasthenia gravis neonatal newborn Obstet occur patients placental plasma platelet possible pregnancy present produced protein rabbit reactivity red cells reported reproductive Rh antibodies Rh disease sensitised sera serum specific antibody sperm spermatozoa stimulation studies suggested surface T-cells thrombocytopenia thymus thyroid tissue titre tolerance transfusion transplantation trophoblast tumour uterine virus vitro women