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Augmentation of Antigen Expression by Recombinant Human
Interferon and the Regulation of DNA Synthesis in 3T3L1 Cell
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2-5A synthetase 3T3 cells Acad Sci USA adenovirus amino acids analysis antigen antiviral antiviral activity assay BALB/c binding Biochem Biol blot c-fos c-myc Cancer cDNA cell growth cell line cells treated cellular chromosome clones cultures cycloheximide cytotoxicity Daudi cells differentiation dsRNA effect of IFN effect of interferon enhanced enzyme extracts fibroblasts Figure gene expression growth factor HuIFN human cells hybrid IFN gamma IFN treatment IFN-a IFN-alpha IFN-induced IFN-treated IFN-y Immunol incubated induced inhibition inhibitory interferon-induced interferon-treated isolated lanes levels lymphocytes lysis macrophages mice mitogens molecular monoclonal antibody monocytes mouse cells mRNA MuIFN murine mutant Natl Acad Sci NK cells Northern blot oncogene phenotype phosphorylation polypeptides probe Proc Natl Acad protein kinase purified recombinant regulation replication response RNase SDS-PAGE sensitivity sequence serum shown specific stimulated studies transcription transfection tumor cells U/ml units/ml untreated viral Virol Virology vitro y-IFN