Intracellular Messengers

Front Cover
C.M. Taylor
Newnes, Dec 2, 2012 - Science - 508 pages
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This important new reference work offers an outstanding collection of articles devoted to the discussion of "intracellular messengers". Extracellular stimuli ("first messengers") bind to receptors on the plasma membrane of cells to trigger changes in the concentration of intracellular messengers ("second messengers") which leads, in turn, to changes in cellular activity. However, the intracellular activities of so called "third messengers" may also be involved complicating the concept of a rigid sequence of events between receptor and response. The preference for the term "intracellular messengers", and, hence, the title of this volume, recognizes that a complex web of interactions between intercellular messengers determines the concentrations and ultimate effects of each.
 

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Contents

CHAPTER 1 STRUCTURE AND FUNCTION OF G PROTEINCOUPLED RECEPTORS
1
CHAPTER 2 STRUCTURE AND FUNCTION OF G PROTEINS
25
CHAPTER 3 THE REGULATION OF ADENYLYL CYCLASE BY RECEPTOROPERATED G PROTEINS
47
CHAPTER 4 RECEPTOR REGULATION OF PHOSPHOINOSITIDASE C
63
CHAPTER 5 GUANYLYL CYCLASELINKED RECEPTORS
89
CHAPTER 6 PROSTAGLANDIN AND THROMBOXANE BIOSYNTHESIS
101
CHAPTER 7 CYCLIC NUCLEOTIDEDEPENDENT PROTEIN KINASES
137
CHAPTER 8 PROTEIN KINASE C
167
CHAPTER 11 REGULATORY FUNCTIONS OF CALMODULIN
265
PHARMACOLOGY BIOCHEMISTRY AND FUNCTION
287
CHAPTER 13 REGULATION OF THE METABOLISM OF 12DIACYLGLYCEROLS AND INOSITOL PHOSPHATES THAT RESPOND TO RECE...
315
CHAPTER 14 Ca2+ EXTRUSION ACROSS PLASMA MEMBRANE AND Ca2+ UPTAKE BY INTRACELLULAR STORES
347
CHAPTER 15 ORGANIZATION OF INTRACELLULAR CALCIUM SIGNALS GENERATED BY INOSITOL LIPIDDEPENDENT HORMONES
407
CHAPTER 16 CALCIUM SIGNALLING AND THE TRIGGERING OF SECRETION IN ADRENAL CHROMAFFIN CELLS
427
CHAPTER 17 INTRACELLULAR MESSENGERS AND THE CONTROL OF PROTEIN SYNTHESIS
447
INDEX
485

CHAPTER 9 STRUCTURE AND FUNCTION OF INOSITOL TRISPHOSPHATE RECEPTORS
199
CHAPTER 10 RECEPTORREGULATED CALCIUM ENTRY
255

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