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Heterotrimeric G Proteins
Low Molecular Weight GTPBinding Proteins
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action addition adenylyl cyclase amino acid amino acid residues arachidonic acid bacteria binding biochemical C-terminal Ca2+ catalytic domain cellular cloned complex components cytoplasmic cytosolic demonstrated enzymatic enzyme eukaryotic eukaryotic cells fatty acids function G proteins gene GPI-anchored proteins GTP-binding proteins GTPase activating guanylyl cyclase homology host cell hydrolysis immunophilins Infect Immun inhibition inhibitor inositol interaction intracellular parasitism Legionella pneumophila ligand lipid listeriolysin lysosomal M.tuberculosis macrophages mammalian MAP kinase mechanism mediate microorganisms molecular mass molecules mutants Mycobacterium neutrophils pathogenic peptide phagocytes phagocytosis phagosomes phos phosphate phosphatidylinositol phospholipase phosphorylation pl20GAP plasma membrane PlcA PlcB protein kinase protein phosphatase protein tyrosine phosphatases PSP1 PSP2B purified Ras proteins reactions receptor region regulation regulatory role second messengers sequence serine/threonine SH2 domains shown signal transduction signaling pathways specific stimulation strain structure studies substrate subunits target tein kinase tion transmembrane tyrosine kinases tyrosine phosphorylation vacuoles