Intracellular Protein Degradation

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IRL Press, 1992 - Cell metabolism. - 61 pages
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Intracellular protein degradation is becoming an area of widely increasing research. It is central to both normal cellular homeostasis and chronic degenerative and viral diseases. Many of the currently incompletely understood human diseases are in fact protein catabolic disorders of some sort. This important book describes the mechanisms of intracellular protein degradation at the molecular and cell biological levels. Topics include the kinetics of protein degradation, lysosomes, cystosolic proteases, the ubiquitin pathway, molecular determinants of protein half-line, and protein degradation in disease. The book will be invaluable to researchers and students in biochemistry, cell biology, and medicine.

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Contents

Further reading
14
Proteolytic systems in bacteria
30
Other signals controlling protein degradation
40
Copyright

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About the author (1992)

R. John Mayer, Professor of Molecular and Cell Biology, both at the Department of Biochemistry, University of Nottingham Medical School, Queen's Medical Centre.

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