Introduction to Bioinformatics
Bioinformatics, the application of computers in biological sciences and especially analysis of biological sequence data, is becoming an essential tool in molecular biology as genome projects generate vast quantities of data. This text provides an introduction to the subject for undergraduates (final year), focussing on two key areas, genojmics and protein sequence analysis. It provides an overview of primary, composite and secondary databases, and gives a brief introduction to the Internet and the World Wide Web.
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4 Facilities used on the Internet
Protein information resources
Genome information resources
9 other sections not shown
accession number ADRENERGIC RECEPTOR algorithm amino acids annotation approach automatic base bioinformatics biological blocks BLOSUM browsers cDNA cell chapter characterised clone Clustal cluster codon complete conserved database searches derived diagnostic DNA sequence domain EMBL EMBnet encoded entry ESTs evolutionary example FastA fingerprint fragment function GenBank gene genetic genome projects Hidden Markov Models homology hydrophobic identical identify indicate insertions interface Internet keyword matches matrix methods Molecular Biology motifs mRNA multiple alignment multiple sequence alignment nucleotide OPSIN packages pairwise Pfam position prediction primary databases PRINTS programs protein families protein folding protein sequence protein sequence database protocol query sequence regions regular expressions relationships residues retrieval rhodopsin Sbjct score secondary databases secondary structure sequence analysis sequence assembly sequence data sequence information server shown in Figure similarity search Smith-Waterman algorithm SWISS-PROT Table techniques tion TRANSFERRIN translation TRFE_XENLA