Introduction to Neuropsychopharmacology
Oxford University Press, Dec 12, 2008 - Medical - 576 pages
Introduction to Neuropsychopharmacology expands on the molecular and cellular foundations of the classic Biochemical Basis of Neuropharmacology, Eighth Edition (Cooper, Bloom, and Roth) by now including the behavioral methods used to study psychoactive drugs in experimental animals and in humans. Authored by four founders of modern neuroscience, this concise and comprehensive text covers the current series of medications used to treat diseases of the brain and nervous system--both psychiatric and neurologic--as well as legal and illegal recreational drugs and the neuroscientific information that explains how these medications act on the brain from the molecular to the clinical level. The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics.
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3 Principles and Methods of Behavioral Pharmacology
5 Amino Acid Neurotransmitters
16 Cognitive Disorders
17 Movement Disorders
20 Recreational Psychoactive Drugs
22 Heroin and Other Opiates
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5-HT receptors action activity addiction adenosine adenylyl cyclase ADHD agonists alcohol amino acid amphetamine animal models antagonists antidepressant antipsychotic anxiolytic autoreceptors axon behavior benzodiazepines brain Ca2+ cannabis catecholamine cells channels Chapter choline cholinergic clinical trials cloned cocaine cognitive compounds cortex cyclase D2 receptors depression disorders dopamine dopaminergic doses drugs Ecstasy endocannabinoids enhance enzyme ethanol excitatory function GABA GABAA receptor gene glutamate H3 receptor histamine human impairment increased inhibition inhibitors interaction intracellular involved levels mechanisms mediated membrane memory metabolism mice modulation molecular monkeys monoamine nerve terminals nervous system neuroleptics neurons neuropeptides neurotransmitter nicotine NMDA receptor norepinephrine nucleus nucleus accumbens opiate pain pathways patients peptides pharmacological phosphorylation postsynaptic potential presynaptic protein rats recep receptor subtypes regulation reinforcement release response reuptake role schizophrenia selective serotonin side effects specific stimulation studies subunit symptoms synaptic syndrome synthesis target tion tissue transmitter transporter treatment tyrosine uptake users