Itch: Basic Mechanisms and Therapy

Front Cover
Gil Yosipovitch, Malcolm W. Greaves, Jr., Alan B. Fleischer, Francis McGlone
CRC Press, Jan 6, 2004 - Medical - 342 pages
Offering details on the pharmacology of itch, techniques of itch evaluation, and neurogenic itch, this reference presents new concepts in the neurophysiology and central mechanisms of itch, animal models of itch, and processing of histamine itch in the human cerebral cortex. The text clarifies itch in systemic and skin disease, exploring renal itch
 

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Contents

Chapter 1 Definitions of Itch
1
Chapter 2 Neurophysiologic Basis of Itch
5
Chapter 3 Pain and Itch
13
Chapter 4 Central Neural Mechanisms of Itch
21
Scratching Away at the Problem
35
Chapter 6 HistamineInduced Discriminative and Affective Responses Revealed by Functional MRI
51
Chapter 7 Central Nervous System Imaging of Itch with PET
63
Neuropeptide Distribution and Its Relationship to Itch
71
Chapter 20 Pruritus Complicating Liver Disease
205
Chapter 21 Itch In HIVInfected Patients
219
Chapter 22 Neuropathic Pruritus
231
Chapter 23 Clinical Features of Itch in Atopic Eczema
241
Chapter 24 Postburn Itch
247
Chapter 25 Pruritus in Lichen Simplex Chronicus and Lichen Amyloidosis
255
Chapter 26 Treatment of Pruritus in Internal and Dermatological Diseases with Opioid Receptor Antagonists
259
Chapter 27 Prospects for a Novel KOpioid Receptor Agonist TRK820 in Uremic Pruritus
279

Chapter 9 Substance P and Itch
87
Chapter 10 Peripheral Opiate Receptor System in Human Epidermis and Itch
97
Figures
102
Chapter 11 Antipruritic Activity of a Novel KOpioid Receptor Agonist TRK820
107
Chapter 12 Putative Role of Cannabinoids in Experimentally Induced Itch and Inflammation in Human Skin
115
Chapter 13 Itch Models in Animals with Special Emphasis on the Serotonin Modelin Rats
131
Chapter 14 Human Itch Models with Special Emphasis on Itch in SLSInflamed and Normal Skin
139
Chapter 15 Microdialysis in Itch Research
147
Chapter 16 Measuring Nocturnal Scratching in Atopic Dermatitis
161
Chapter 17 Itch Questionnaires as Tools for Itch Evaluation
169
Chapter 18 Epidemiology of Itching In Skin and Systemic Diseases
183
New Perspectives and Insights from Recent Trials
193
Chapter 28 Treatment of Pruritic Skin Diseases with Topical Capsaicin
287
Chapter 29 Mechanistic and Clinical Assessment of Zangrado an Extract of the Amazonian Ethnomedicine Sangrede Grado for the Treatment of Itch
305
A New Approach for Patients with Inflammatory Disease
315
Chapter 31 5HT3 Receptor Antagonists as Antipruritics
325
Chapter 32 Cutaneous Nerve Stimulationin the Treatment of Localized Itch
335
Chapter 33Psychosomatic Aspects of Pruritus
343
Chapter 34 On Psychological Factors Affecting Reports of Itch Perception
351
Chapter 35 Itching as a Focus of Mental Disturbance
369
Index
377
Back Cover
394
Copyright

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About the author (2004)

Dr. Fleischer is a reviewer to the JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY and ARCHIVES OF DERMATOLOGY. He is an editor on the JOURNAL OF GERIATRIC DERMATOLOGY, SKIN And AGING and is the author of 20 COMMON PROBLEMS IN DERMATOLOGY, a book recently published by McGraw-Hill.

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