Landmark Papers in Clinical Chemistry

Front Cover
Richard M. Rocco
Elsevier, Nov 15, 2005 - Science - 522 pages
This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.

Landmark Papers addresses:
*The origin of the home pregnancy test available today in every drugstore
*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize
*The scientists who worked on the US Government’s crash program at the start of WWII to find a substitute for the malaria drug quinine
*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients
*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide
*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine
*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control

*First book of this kind dedicated to clinical chemistry
*Thirty-nine articles that have shaped the field today
*A survey of the major developments in the field clinical chemistry in the 20th century
 

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Contents

Immunoassay Technology
1
Therapeutic Drug Monitoring TDM
63
Enzymology
131
Specific Analytes
163
Instrumentation and Techniques
299
Chemometrics
399
Molecular Diagnostics
471
Overview of the Publication Source of the Original Articles
495
Author Index
499
Subject Index
501
Copyright

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About the author (2005)

Following a 25-year career in clinical chemistry, R M Rocco currently teaches graduate courses in the biomedical laboratory sciences at San Francisco State University. Landmark Papers grew out of a graduate seminar in landmark papers in biotechnology. Dr Rocco has extensive experience in directing pharmaceutical and clinical chemistry research and development groups.

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