Lipoxygenases and Their Products
Stanley T. Crooke, Angela Wong
Academic Press, 1991 - Science - 300 pages
Lipoxygenases and Their Products provides a cogent summary of the advances in understanding lipoxygenases and their products, emphasizing their pharmacology and pathophysiology; regulation and structure; physiological role; and receptors and receptor antagonists. This text also reviews the literature where specific receptor antagonists (as opposed to enzymatic inhibitors) have been used to characterize the pharmacologic action and the pathophysiologic roles of some of lipoxygenase products of arachidonic acid metabolism. This book is organized into 11 chapters and begins with an overview of th ...
What people are saying - Write a review
We haven't found any reviews in the usual places.
5-HPETE 5-lipoxy 5-lipoxygenase inhibitors Acad Acta activity agonist airway antigen arachidonate 5-lipoxygenase arachidonic acid assay binding Biochem Biol biological Biophys biosynthesis bronchoconstriction Ca2+ calcium cells cellular Chem compounds concentrations contraction COOH cyclooxygenase Dermatol disease effects eicosanoids enzymatic enzyme fatty acids Ford-Hutchinson formation Furukawa genase Goetzl guinea pig guinea pig lung Hogaboom human leukocytes human PMNs hydroperoxide Immunol inactivation induced inflammatory inhibition intracellular ionophore isolated kinetic leuko leukotriene B4 lipid lipoxins LTA4 LTB4 LTBA LTC4 LTD4 LTDa LTE4 LXA4 mediators membrane metabolism metabolites Natl neutrophils Ochi oxygen pathway peptidoleukotrienes Pharmacol pharmacological phospholipids platelets polymorphonuclear leukocytes porcine leukocytes potent Proc Prostaglandins protein psoriasis purified rabbit reaction receptor antagonists release renal responses reticulocyte role Rouzer and Samuelsson Samuelsson Serhan Shimizu SK&F skin smooth muscle specific stimulation studies substrate synthase synthesis thromboxane tion tissues trachea triene Ueda vascular vitro vivo Yamamoto Yoshimoto