Lithium and the Cell: Pharmacology and Biochemistry

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Nicholas J. Birch
Academic Press, Dec 2, 2012 - Medical - 368 pages
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This up-to-date compilation addresses the scientific problems of determining a mode of action of lithium and provides a cross-disciplinary perspective. In addition to psychiatrists interested in the therapeutic uses of lithium, it will also be of interest to biochemists using lithium as an inhibitor of phosphoinositide signaling, immunologists studying lymphocytes, and dermatologists studying viral replication in the skin.
 

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Contents

Chapter 2 Exotic Effects of Lithium
7
Chapter 3 New Approaches to Identification of MetalLigand Interactions in Solution and Application to Some Lithium Complexes
35
Chapter 4 Methods for the Determination of the Distribution of Lithium at the Histological and Cytological Levels
59
Chapter 5 Studies on Li+ Transport using 7Li and 6Li Nuclear Magnetic Resonance
85
Chapter 6 Effect of Lithium on Viral Replication
99
Chapter 7 Effect of Lithium on Human Neurotransmitter Receptor Systems and G Proteins
113
Chapter 8 Lithium and the Phosphoinositide Signalling System
121
Chapter 9 Lithium in the Cellular Environment
159
Comparison and Contrast with Carbamazepine
199
Chapter 13 Gastrointestinal Absorption of Lithium
243
Chapter 14 Renal Elimination of Lithium
249
Chapter 15 Lithium and Essential Fatty Acid Metabolism in Psychiatric Disorders Herpes Virus Infections and Seborrhoeic Dermatitis
273
Insights into Biological Regulation and Diversity
289
Chapter 17 Bioavailability of Lithium Formulations
317
Chapter 18 The Switch Process and the Effect of Lithium
327
Index
343

Chapter 10 Intracellular Concentrations of Lithium as Studied by Nuclear Magnetic Resonance Spectroscopy
175
Chapter 11 Effect of Lithium on Blood Cells and the Function of Granulocytes
185

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