Cellules Hépatiques Et Médicaments
Libbey, Jan 1, 1988 - Liver - 494 pages
This book contains the 17 lectures given at the International Symposium on Liver Cells and Drugs held in Rennes on 7 to 10 July 1987 as well as 50 communications presented at the poster sessions.
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J P Benhamou
O F W James M D Rawlins H Wynne K W Woodhouse
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acetaminophen acid albumin amineptine animals antibodies antigens assay bile Biochem Biol biotransformation buffer caffeine calcium carbamazepine CCI4 cDNA cell lines Cells and Drugs cellular Chem chemical cholestasis Clin Colloque INSERM/John Libbey compounds concentration conjugation covalent binding culture medium cultured hepatocytes cultured rat hepatocytes cytochrome P-450 cytotoxicity decreased DMSO dose drug metabolism drug-induced effect enzymes epoxide epoxide hydrolase erythromycin ethanol glucuronide glutathione GSH transferases Guengerich Guguen-Guillouzo Guillouzo halothane halothane hepatitis hepatocyte cultures hepatoma hepatoma cells hepatotoxicity HPLC human hepatocytes human liver increased incubation induced inhibition INSERM INSERM/John Libbey Eurotext intracellular isolated hepatocytes isozymes Larrey Libbey Eurotext Ltd lipid liver liver cells liver microsomes membrane metabolites method microsomes monooxygenase mRNA oxidation paracetamol pathways patients perfusion Pessayre Pharmacol phenobarbital plasma primary culture prolidase protein rabbit rat liver Ratanasavanh reaction reactive metabolites serum specific studies substrate subunit synthesis theophylline tienilic acid toxicity treatment valproate vitamin vitro vivo xenobiotics