Lymphoproliferative Diseases of the Skin
M. Goos, E. Christophers
Springer Berlin Heidelberg, Feb 1, 1982 - Medical - 298 pages
In recent years immunobiology has witness aspects on the background of various meth ed most remarkable achievements and the ods applied, as well as clinicopathologic im understanding of lymphomas and leukemias plications. A special chapter is addressed to is greatly increased. Knowing that these "Pagetoid Reticulosis" elucidating the neoplasms are essentially immunoprolif various views on the cytogenesis of this neo plasm. For the same reason, a contribution erative diseases extended the dermatological views of the corresponding skin tumors. on "Merkel Cell Neoplasms of the Skin" has Sophisticated techniques and new im been included because these tumors have munological methods now enable us to been mistaken for pagetoid reticulosis. analyze and classify cutaneous malignant The last chapter on "Cooperative Study lymphomas far better than before. As a Groups, Staging and Treatment" leads off consequence this has produced a vast lit with the signmcant contribution from the erature on this subject in the last few years. Kiel Lymphoma Study Group (G. Brit For those who are not so familiar with mod tinger}. 1t deals with the results of a prospec em immunological thinking, it has become tive study of nodal lymphomas which were increasingly difficult to keep abreast with classilled according to the Kiel Classmca these developments, and a comprehensive tion. Treatment protocols applied to skin review of this subject appeared to be needed. lymphomas are reported from Cooperative This is the purpose of the present book.
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Origin and Functions of Langerhans Cells
Chu A Berger C L Lynfield Y Esseesse J Edelson R L
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abnormal antigens Arch Dermatol atypical benign biopsies bone marrow Braun-Falco Burg G Cancer cell lines cell lymphomas cell type centroblastic centrocytes chemotherapy chronic lymphocytic classification clinical CTCL cutaneous lymphomas cutaneous T cell cytes cytoplasm dendritic reticulum cells dermatopathic dermis diagnosis differentiation disease Edelson epidermis epidermotropic extracutaneous follicles follicular germinal centers helper helper T cells histiocytosis histologic human HuTLA hybridoma immuno immunoblastic immunocytoma immunoglobulin immunologic involvement Kiel Langerhans cells Lennert leukapheresis lymph node lymphadenopathy lymphoblastic lymphography lymphoid cells macrophages malignant histiocytosis malignant lymphomas membrane Merkel cell monoclonal antibodies mononuclear cells morphological mycosis fun mycosis fungoides myeloma neoplasm nodules normal nuclear nuclei OKT4 OKT8 pagetoid reticulosis Pathol patients with mycosis peripheral blood phomas plaques proliferation pseudolymphomas PUVA receptors remission Sézary cells Sézary syndrome Sézary's skin biopsy skin lesions stage staining T-lymphocytes Table therapy thymus tients tion tissue tumor cells ultrastructural vitro Vloten