Magnetic Source Imaging of the Human Brain

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Zhong-Lin Lu, Lloyd Kaufman
Taylor & Francis, Oct 17, 2003 - HEALTH & FITNESS - 416 pages
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This book is designed to acquaint serious students, scientists, and clinicians with magnetic source imaging (MSI)--a brain imaging technique of proven importance that promises even more important advances. The technique permits spatial resolution of neural events on a scale measured in millimeters and temporal resolution measured in milliseconds. Although widely mentioned in literature dealing with cognitive neuroscience and functional brain imaging, there is no single book describing both the foundations and actual methods of magnetoencephalopgraphy and its underlying science, neuromagnetism. This volume fills a long-standing need, as it is accessible to scientists and students having no special background in the field, and makes it possible for them to understand this literature and undertake their own research.

A self-contained unit, this book covers MSI from beginning to end, including its relationship to allied technologies, such as electroencephalography and modern functional imaging modalities. In addition, the book:
*introduces the field to the non-specialist, providing a framework for the rest of the book;
*provides a thorough review of the physiological basis of MSI;
*describes the mathematical bases of MSI--the forward and inverse problems;
*outlines new signal processing methods that extract information from single-trial MEG;
*depicts the early, as well as the most recent versions of MSI technology;
*compares MSI with other imaging methodologies;
*describes new paradigms and analysis techniques in applying MSI to study human perception and cognition, which are also applicable to EEG; and
*reviews some of the most important results in MSI from the most prominent researchers and laboratories around the world.
 

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Contents

1 Basics of Neuromagnetism and Magnetic Source Imaging
1
2 Toward Understanding the Physiological Origins of Neuromagnetic Signals
43
3 Forward Problem Solution of Magnetic Source Imaging
77
Search for Inverse Solutions
101
5 Techniques for Investigating and Exploiting Nonlinearities in Brain Processes by Recording Responses Evoked by Sensory Stimuli
135
Localization and SingleTrial Response Onset Detection
159
7 Toward NoiseImmune Magnetoencephalography Instrumentation
203
Sam Williamsons Vision Brought to Life
217
From Pioneering Studies to Functional Brain Imaging
243
11 Optical Imaging of Brain Function and the Relation Between Neuronal Activity and Hemodynamics in Health and Disease
259
The Interneuron Hypothesis
281
Magnetoencephalography Habituation and Psychophysics
319
14 Clinical Applications of Brain Magnetic Source Imaging
343
Epilogue
365
Author Index
377
Subject Index
393

Highlights of Neuromagnetic Brain Research in Finland
231

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About the author (2003)

Zhong-Lin Lu is Distinguished Professor of Social and Behavioral Sciences, Professor of Psychology, and Director of the Center for Brain and Cognitive Sciences at The Ohio State University.

Lloyd Kaufman has written, produced, and/or directed more than 25 films, including "The Toxic Avenger", "Sgt. Kabukiman NYPD", and "Terror Firmer". He is president of Troma Entertainment. This is his second book.

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