Malaria: Obstacles and Opportunities

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Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death.
This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities.
The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the

  • Nature, clinical manifestations, diagnosis, and epidemiology of malaria.
  • Biology of the malaria parasite and its vector.
  • Prospects for developing malaria vaccines and improved treatments.
  • Economic, social, and behavioral factors in malaria control.


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Conclusions and Recommendations 1
Background 22
Overview 37
Clinical Medicine and the Disease Process 56
Diagnostic Tests 73
Parasite Biology 90
Vector Biology Ecology and Control 118
Drug Discovery and Development 144
Vaccines 169
Epidemiologic Approaches to Malaria Control 211 11 Economics of Malaria Control 237
A Paradigms 279

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