Malignant Liver Tumors: Current and Emerging Therapies

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Pierre-Alain Clavien
John Wiley & Sons, Sep 23, 2011 - Medical - 576 pages
This comprehensive and critical review of current and established treatment modalities for malignant liver tumors is designed to help you sort through the proliferation of competitive approaches and choose the best treatment options for your patient. Dr. Clavien and his contributors consider all the options – radiological, surgical, pharmaceutical, and emerging/novel therapies – and help you find the best single or combined therapy.

Building on the success of the previous edition, this extremely thorough revision:

  • features a new section on Guidelines for Liver Tumors, where you will find specific strategies for treating common liver malignancies; the guidelines were prepared by the Associate Editors and take into account national and international society guidelines
  • reflects actual practice by taking a multidisciplinary approach, with contributions from international experts who have extensive experience with this patient population
  • achieves comprehensive and balanced coverage by having each chapter reviewed by the Editor, Deputy Editor, two Associate Editors, and at least one external reviewer
  • includes 16 new chapters that cover liver anatomy, histologic changes in the liver, epidemiology and natural history of HCC, CCC and colorectal liver metastases, strategies of liver resection, and economic aspects as well as novel therapies
  • facilitates the kind of daily interaction among hepatologists, hepatic surgeons, medical oncologists, radiotherapists, and interventional radiologists that is essential when treating patients with complex liver malignancies

In 44 chapters organized into six major sections, the book covers the full range of liver tumors. The perfect blend of evidence and experience, Malignant Liver Tumors: Current and Emerging Therapies, 3rd Edition, illuminates the path to better patient care.


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From Promethean to Modern Times
Hepatic Anatomy and Terminology
Histology and Pathology of Normal and Diseased Liver
Pathology of Primary and SecondaLy Malignant Liver Tumors
Internal Radiation Therapy for Liver Tumors
Selfassessment answers
Transplantation for liver metastases of neuroendocrine tumors
Epidemiology Etiology and Natural History
Gallbladder Cancer
Colorectal Liver Metastases

Selective Continuous Intraarterial Chemotherapy for Liver
Isolated Hepatic Perfusion and Percutaneous Hepatic
Liver transplantation for hepatocellular carcinoma
Liver Resection of Colorectal Liver Metastases
Laparoscopic Liver Resection
Repeat Resection for Liver Tumors
Cryoablation of Liver Tumors
Prognostic factors after cryotherapy
Ethanol and Other Percutaneous Iniection Modalities in
Transplantation for Liver Tumors
Signaling Pathways and Rationale for Molecular Therapies
Novel Therapies Targeted at Signal Transduction in Liver
Induction of Apoptosis in Liver Tumors
Antiangiogenic Agents for Liver Tumors
Alternative and CompIementaLy
Liver Metastases from Endocrine Tumors
Uncommon Primary and Metastatic Liver Tumors
Liver Tumors in Special Populations
WeiChen Lee and MiinFu Chen
Selfassessment answers
Selfassessment questions

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About the author (2011)

Pierre-Alain Clavien

Department of Visceral and Transplant Surgery, University Hospital Zurich, Switzerland

Associate Editors:
Tadatoshi Takayama
, Second Department of Surgery, Faculty of Medicine, University of Tokyo, Japan

CM Lo, Liver Transplant Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong

R. Chari, Associate Professor of Surgery and Cancer Biology, Division Chief of Hepatobillary Surgery and Liver Transplantation, Staff Surgeon, Veterans Affairs Medical Center, Vanderbilt University Medical Center, Nashville, USA

M. Morse, Associate Professor, Duke University Medical School, Durham, USA

J. Llovet, Barcelona-Clínic Liver Cancer Group, Liver Unit, Institut d'Investigacions Biomédiques August Pi I Sunyer, Hospital Clínic, University of Barcelona, Catalonia, Spain

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