Management of Chronic Viral Hepatitis
Hepatitis, the leading indication for liver transplantation, is a straight-forward disease when it comes to diagnosis: it is a disease of pathology and is diagnosed by liver biopsy, with the result being either positive or negative. There is only one effective treatment: interferons. Nonetheless, new interferons are appearing on the market and Drs
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active antibodies antigen antiviral assessed associated beneﬁt cause chronic hepatitis chronic viral hepatitis clinical trials co-infection combination therapy common conﬁrm cryoglobulinaemia delta virus infection diagnosis difﬁcult dose drug False ﬁbrosis ﬁrst genome genotypes HBeAg HBeAg-negative chronic hepatitis HBsAg hepatitis B virus hepatitis B-related hepatitis delta virus hepatocellular carcinoma hepatocytes histological identiﬁed immune response immunoactive phase immunohistochemical staining immunosuppression immunosurveillance phase immunotolerant phase increase interface hepatitis interferon interferon and ribavirin interferon therapy lamivudine lamivudine therapy large cell dysplasia lead lesions liver biopsy liver cell cancer liver damage liver disease liver function tests lobular inﬂammation modiﬁed mutant natural history patients with chronic patients with cirrhosis patients with hepatitis pegylated interferon-alpha-2b pegylated interferons portal tract presence progression protein ribavirin risk scoring system seen seroconversion signiﬁcant speciﬁc surface antigenaemia thyroid transmission transplantation treatment tumour type I interferons ultrasound usually vaccination viraemia viral proteins viral replication virus DNA viruses