Management of Psoriasis

Front Cover
Nikhil Yawalkar
Karger Medical and Scientific Publishers, 2009 - Medical - 195 pages
Treatments for psoriasis, besides affecting the skin, may be associated with various comorbidities (for instance, depression, psoriatic arthritis, Crohn's disease and, in severe psoriasis, metabolic syndrome and cardiovascular diseases), which often presents a therapeutic challenge to physicians.Written by renowned experts, this volume gives a comprehensive overview of psoriasis and its various comorbidities. It describes the treatment modalities for mild and moderate-to-severe psoriasis, including topical, phototherapeutic and conventional systemic treatments (e.g. acitretine, methotrexate and cyclosporine), as well as biological therapies (e.g. alefacept, efalizumab, etanercept, adalimumab and infliximab). The chapters on biological therapies focus on key safety issues. Further chapters focus on such topics as the management of childhood psoriasis and psoriasis in distinctive locations, such as the scalp, face, flexures, palm/soles and nails. Finally, future therapeutic modalities, with the focus on small molecules and potential biological therapies, are discussed.This publication will make significant reading to dermatologists and all physicians dealing with psoriasis, such as general practitioners, psychiatrists, rheumatologists, cardiologists and diabetologists.
 

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Contents

Clinical Spectrum and Severity of Psoriasis
1
Impact of Comorbidities on the Management of Psoriasis
21
Topical Treatment of Psoriasis
37
Practice of Phototherapy in the Treatment of ModeratetoSevere Psoriasis
59
Retinoids Methotrexate and Cyclosporine
79
Monitoring Patients Treated with Efalizumab or Alefacept
95
Management of Severe Psoriasis with TNF Antagonists
107
Therapies for Childhood Psoriasis
137
Management of Difficult to Treat Locations of Psoriasis
160
Future Perspectives in the Treatment of Psoriasis
172
Author Index
190
Subject Index
191
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