Maternal-fetal Toxicology: A Clinician's GuideGideon Koren For health professionals who are asked by women and their families to provide answers on potential reproductive effects of xenobiotics and radiation, this volume presents the approaches and clinical tools developed by the multidisciplinary team at the Motherisk Clinic in Toronto to inform, counsel, and follow up pregnant women exposed to drugs, chemicals, or radiation in pregnancy. This revised and expanded edition adds several novel aspects, such as the maternal-fetal toxicology of medicinal plants, developmental risk assessment, and biological markers of intrauterine exposure to drugs of abuse. This edition also includes clinical cases at the beginning of most chapters, with answers at the end. Annotation c. by Book News, Inc., Portland, Or. |
Contents
Changes in Drug Disposition in Pregnancy | 3 |
Teratogenic Drugs and Chemicals in Humans | 33 |
Monotherapy on Infants Development | 49 |
Copyright | |
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abnormalities acetaminophen acid adverse effects adverse reac agents alcohol amniocentesis anomalies assessment associated babies Bendectin benzodiazepines birth defects birth weight blood breast milk breastfeeding Canada Carbamazepine cells chemicals chromosome cleft Clin Pharmacol clinical cocaine concentrations congenital malformations cotinine developmental diagnosis diazepam disease dose drug Engl excretion exposed exposure fetal fetus fluoxetine genetic Gideon Koren growth retardation Health Hospital for Sick human increased risk infants born ingestion intrauterine lactation Lancet lead levels lithium maternal metabolite methadone mg/d Motherisk Program mothers nancy narcotic neonatal neural tube defects newborn normal Obstet Gynecol offspring Ontario overdose oxytocicity patients Pediatr perinatal Pharmacological phenytoin placenta plasma poisoning potential preg pregnancy pregnancy outcome pregnant women prenatal radiation reported reproductive serum spontaneous abortions stillbirth symptoms syndrome Table 1 Continued teratogenic teratogenic risk Teratology therapeutic therapy tion Toronto toxicity Toxicol Toxicology treatment trimester ultrasound utero weeks withdrawal woman