Advances in Enzymology and Related Areas of Molecular Biology, Part A: Mechanism of Enzyme Action
Daniel L. Purich
John Wiley & Sons, Apr 22, 1999 - Science - 296 pages
Biological catalysis plays a dominant role both in fermentation and industrial process chemistry. This collection of chapters, written by a well-known biochemist and enzymologist, should serve as an invaluable reference to those investigators seeking to optimize the application of enzymatic catalysis for commercial purposes.
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acceptor active site activity adenine adenylate kinase adenylosuccinate adenylosuccinate synthetase amino acid amino group AMPSase analogue aspartate Biochemistry Biochim Biophys Acta Biol Chem biosynthesis catalysis catalytic power cDNA cells Chem cloned complex conformational changes crystal structure cystamine cysteine divalent cation domain enzymatic enzyme enzyme-bound enzyme-substrate compound equation Escherichia coli Figure formation Fromm HJ gene glutamate glutamine Griffith OW GSH levels GSH synthesis hadacidin human hydrogen bonds inactivation inhibition inhibitor interactions intermediate compound isozyme JBiol kinetic kynureninase kynurenine L-cysteine L-glutamate ligands liver loop mammalian mechanism metabolism Michaelis Mildvan mole molecular mononucleotide Mulcahy Mut'ſ mutagenesis mutant Mutt enzyme nicotinic NMN adenylyltransferase NMP kinases nucleotide oxygen pathway peroxidase phosphate phosphoribosyltransferase phosphoryl protein Purification purine pyridine pyridine nucleotide quinolinate residues role Schulz specific studies substrate subunit tion transition tumor typhimurium uncatalyzed reactions Y-GCS Y-GCSh yeast zyme