Mechanism of Tumor Growth in Crowngall

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U.S. Government Printing Office, 1927 - Cancer - 55 pages

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Page 4 - McCuLLOCH, L. 1912. The structure and development of crown gall: a plant cancer.
Page 4 - Smith had concluded that it would seem . . . that in local osmotic action (possibly in some stages chemical action also) of various substances (aldehyde, acetone, alcohol, acids, alkalies) thrown into cells and diffusing from them in various directions, as the result of the metabolism of a feeble intracellular parasite or symbiont together with the resultant counter movements of water and food supply we have, in crowngall at least and presumptively also in...
Page 3 - I have established my original hypothesis — viz, that dilute ammonia causes intumescences and have rendered it probable that ammonia liberated within the cell in small quantities by the imprisoned bacteria must be one of the causes of the excessive and abnormal cell proliferation in crowngall. Probably amin compounds also help to determine it. Since an acid and an alcohol are likewise produced by the crowngall bacteria and this alcohol and this acid (as well as...
Page 4 - CHEMIST. [This report was received too late to be inserted in its proper place in the text.
Page 3 - Jan. ig, 1917 Mechanism of Tumor Growth in Crowngall 1 83 Similar results were obtained on cauliflower leaves by exposure to the vapor of secondary methylamine (PI. 46, 62, 63, 64). Also on cauliflower plants exposed to the vapor of primary ethylamine the younger leaves showed distortions and thickenings of the parenchyma with changes in the palisade tissue quite suggestive of curly top of sugar beets, mosaic of tobacco, and similar diseases of undetermined origin but suspected of being due to parasites...

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