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Structural analysis of acute liver injury
Zonation of hepatocellular injury
25 other sections not shown
Acad activity acute agents alcohol alterations animals antagonists antibodies anticalmodulin antigen arachidonic acid ATPase bacterial bile flow binding Biochem Biol biological Biophys bromobenzene calmodulin carbon tetrachloride cell death cell injury cell necrosis cellular Chem chemical chronic concentration cultured hepatocytes cytochrome P450 cytoplasmic cytosolic cytosolic Ca2+ damage dose drugs effects endoplasmic endotoxin enzyme ethanol experimental extracellular Ca2+ Figure fraction function glutathione heparan sulphate hepatic hepatocellular injury hepatocytes homeostasis human increase incubated induced infection inhibition inhibitors inositol interaction intracellular isolated hepatocytes leukotriene leukotriene C4 lipid peroxidation lipopolysaccharide liver cell liver disease liver injury mechanism metabolism mice microsomal mitochondria mitochondrial Natl necrosis necrotic neutrophils nitrendipine nucleotide oxidation oxygen paracetamol Pathol phalloidin Pharmacol phosphodiesterase phospholipase A2 plasma membrane platelets Proc prostaglandin protein radicals reaction receptor release response role Shwartzman sinusoidal specific stimulated studies synthesis tissue toxic toxin trifluoperazine uptake verapamil vesicles viral virus vitro vivo