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The Streptomyces DDcarboxypeptidasetranspeptidase system as a model
On distamycin A and related compounds selective antiviral agents
Analogues of cyclic AMP and their biological actionsTH POSTERNAK
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3-lactam antibiotics Acad acceptor acid residues action acylation amino acids amino group antibacterial antibiotics atom bacterial binding Biochem bioisosteres Biol biological activity bond calculations carboxypeptidase catalytic activity Cehovic cephalosporins Chem Chemical coli complex compounds concentration conformation correlation cyclic AMP D-Ala D-alanine derivatives of cAMP des-Lys determined diphenhydramine distamycin drug effect eicosapeptide electrons enzyme Figure guanidination harmaline hormone hydrochloride hydrolysis hydrolyzed indole infected inhibition inhibitory activity interaction interpeptide isosteres kinetic lipophilic Marchiori F Medicinal Chemistry method mg/kg molecular orbital molecule Moroder nitrogen nucleotides obtained parameters penicillin penicillins and cephalosporins peptide donor peptidoglycan physicochemical position properties protein Proton R61 enzyme reaction receptor release ring RNase Rocchi S-peptide S-protein Scoffone serotonin shown side chain Streptomyces structure studies styrene substituted substrate Sulfonamide sulfur sulfur analog synthesis Table tetrapeptide tion transpeptidase tryptamine values vivo whole cell