Metabolising: Webster's Facts and Phrases

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Icon Group International, Incorporated, Dec 19, 2008 - 33 pages
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Nonfiction Usage Patent UsageDisease Treatment: Patented by Clair Adcocks, Claes Bavik, Michael Cork, Gordon Duff, Rachid Tazi-ahnini and Simon Ward on December 4, 2001. Abstract: We describe a method of alleviating or preventing a tachyphylactic response to an agent in a individual, the method comprising administering to the individual an antagonist of a metabolic enzyme which is induced as a result of exposure of the individual to the agent, in which the enzyme activity is capable of metabolising the agent.Genetic sequences encoding flavonol synthase enzymes and uses therefor: Patented by Timothy Albert Holton and Lisa Ann Keam on March 2, 1995. Abstract: The present invention relates generally to genetic sequences encoding flavonoid pathway metabolising enzymes and in particular enzymes having flavonol synthase activity and their use such as in manipulating production of pigmentory molecules in plants. More particularly, the present invention provides genetic sequences encoding flavonol synthase (FLS).Genotyping Cytochrome Expression: Patented by Aimee D. Paulussen Catherine and Martin Armstrong on December 22, 1999. Abstract: There is disclosed a method of identifying subjects having a high or low drug metabolising phenotype associated with cytochrome CYP3A5 expression, which method comprises screening genomic DNA from said subject for the presence or absence of one or more polymorphic variants in a transcription regulatory region of the sequence encoding CYP3A5. Oligonucleotide molecules for carrying out the screening are also provided.Imidazo 1,3,5 Triazinones and the Use Thereof: Patented by Ulrich Niewouml;hner, Helmut Haning, Thomas Lampe, Mazen Es-sayed, Gunter Schmidt, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn and Karl-Heinz Schlemmer on December 12, 2000. Abstract: The invention relates to novel imidazo[1,3,5]triazinones of the general formula (I), to a method for their production and to their use as medicaments, in particular as inhibitors of cyclic GMP metabolising phosphodiesterases.Novel Imidazo[1,3,5]triazinones and the Use Thereof: Patented by Ulrich Niewouml;hner, Helmut Haning, Thomas Lampe, Mazen Es-Sayed, Gunter Schmidt, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn and Karl-Heinz Schlemmer on December 12, 2000. Abstract: The invention relates to novel imidazo[1,3,5]triazinones of the general formula (I), to a method for their production and to their use as medicaments, in particular as inhibitors of cyclic GMP metabolising phosphodiesterases.Prevention and Treatment of Tachyphylactic Response: Patented by Clair Adcocks, Claes Bavik, Michael Cork, Gordon Duff, Rachid Tazi-ahnini and Simon Ward on December 4, 2001. Abstract: We describe a method of alleviating or preventing a tachyphylactic response to an agent in a individual, the method comprising administering to the individual an antagonist of a metabolic enzyme which is induced as a result of exposure of the individual to the agent, in which the enzyme activity is capable of metabolising the agent.Use of Cyp1b1 Inhibitors for Treating Cancer: Patented by Graeme I. Murray, William T. Melvin and Morag Mcfadyen on February 9, 2001. Abstract: CYP1B1 proteins and their role in metabolising or inactivating anti-cancer drugs is disclosed, together with compositions for treating cancer comprising a substance capable of inhibiting CYP1B1 protein and an anti-cancer drug (e.g. docetaxel, paclitaxel, flutamide, tamoxifen, mitoxantrone, doxorubicin or daunomycin).Waste Water Treatment Method Using a Mixture of Enzymes: Patented by Philippe Ledent, Valeacute;rie Debois, Magali Czochara and Gordon Blackman on February 28, 2001. Abstract: The invention concerns a waste water treatment method for enhancing the metabolising kinetics of organic matters by micro-organisms present in waste water. The invention is characterised in that it consists in adding to said waste water a cleaning product comprising a mixture of enzymes whereof the concentrati

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