Metabolizing: Webster's Facts and Phrases

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Icon Group International, Incorporated, Dec 19, 2008 - 98 pages
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Nonfiction Usage Journalism UsageEarth's - News: March 23, 2002 - Headline: Scientists Try to Preserve Exotic Crops. Excerpt: Walters: Well, that's a really amazing thing of life, Is that here's something that's alive, but you can't tell it. It doesn't have any of the mechanisms that we understand as living. They don't grow, they don't reproduce. They're not metabolizing, so they just don't look alive, but they are alive. I mean, there's some really fundamental questions we're asking.Our World - News: September 7, 2007 - Headline: Our World - 8 September 2007. Excerpt: VENTER: There's one gene associated with metabolizing environmental toxins. One of my parents had no copies of that gene and one had one. So one of the chromosomes I have is blank at that spot, and the other has that gene.University of Chicago - News: March 17, 2006 - Headline: Scientists Say Humans Continue to Evolve. Author: Rosanne Skirble. Excerpt: Their study revealed widespread evidence of biological adaptation across the human genome in response to changes in climate conditions, new habitats and population densities over the last 5,000 to 10,000 years. For example, in Europeans we see five different genes that play a role in skin coloring, and it seems likely that these signals are reflecting the adaptation of Europeans to more northerly latitudes as they spread north and were getting less sunlight, he says. Light skin pigmentation is believed to be important for metabolizing Vitamin D, which protects against rickets.Patent UsageA Retinoic Acid Metabolizing Cytochrome P450: Patented by Jan Wisniewski, P. M. Petkovich and Heather Ramshaw on May 23, 2002. Abstract: The present invention provides a novel retinoic acid metabolizing cytochrome P450, P450RAI-3, that is predominantly expressed in the adrenal gland. Methods for and uses of the new polynucleotide, polypeptide, fragments thereof and modulators thereof, include the treatment of cancer.A Sulfur Metabolizing Gene from the Roots of Onion: Patented by Meeghan D. Pitherndash;joyce, Martin L. Shaw, Colin C. Eady, John Mccallum, Jane E. Lancaster and Ited G. New Zealand Institute For Crop & Food Research Lim Lincoln on November 26, 1999. Abstract: The invention provides a novel alliinase gene isolated from the roots of onion plants. Also provided is the enzyme encoded by the gene. A binary vector including the gene is described together with its use to transform Allium species, particularly onions. The invention also provides a method of manipulating alliinase levels in plants.Agents that bind to and inhibit human cytochrome P450 2D6: Patented by Harry V. Gelboin, Frank J. Gonzalez and Kristopher W. Krausz on January 3, 1997. Abstract: The invention provides monoclonal antibodies and other binding agents to human cytochrome P450 2D6 having advantageous properties, including capacity substantially to inhibit enzyme activity of human cytochrome P450 2D6 and lack of specific binding to other human cytochromes P450. The binding agents of the invention are useful in methods for screening drugs for metabolism by cytochrome P450 2D6, and in methods of screening individuals for a poor metabolizing human P450 2D6 phenotype.Assay for Screening Compounds for Inducing Drug Metabolizing Enzymes: Patented by Ulrich Brinkmann, Leszek Wojnowski, Oliver Burk and Ilka Brehm on July 13, 2001. Abstract: Described are methods for screening inducers of genes involved in drug metabolization. In particular, an in vitro cell based assay is provided with cells derived from the cell line LS174T. Described are also methods for identifying and obtaining drugs for therapy of disorders related to the expression of the cytochrome P450 (CYP), gene family. Furthermore, kits suitable for such methods are provided.BACTERIA THAT METABOLIZE PHENYLACETATE THROUGH MANDELATE: Patented by Steven D. Geusz and David M. Anderson on December 1, 1987. Abstract: Bacteria that metabolize phenylacetate along a mandelate-to

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